Folate Gold - 800 mcg (Organic, Whole-food, Plant-based)
Whole-Food Folate GoldWhole-Food Folate from Lemon Peel
Folate, also known as vitamin B9, is most noted for its role in supporting a healthy pregnancy and fetal development. Contrary to popular opinion, folic acid and folate are not the same, and the terms should not be used interchangeably. Folic acid refers to the oxidized, synthetic compound used in dietary supplements and food fortification, whereas folate refers to the various tetrahydrofolate (THF) derivatives naturally found in food.
Unlike natural folates (from food sources) that are metabolized to THF in the small intestines, synthetic folic acid must undergo initial reduction and methylation in the liver, where it is converted to THF in the presence of the enzyme dihydrofolate reductase (DHFR). However, because DHFR has low activity in the human liver, often insufficient amounts of synthetic folic acid are converted to the THF form, resulting in unnatural and potentially harmful levels of unmetabolized folic acid entering the circulatory system. So, when adequate folate consumption from dietary sources is not an option, it is best to supplement with whole-food folate from food sources to minimize risk of deficiency.